ACUTE TOXICITY EVALUATION OF PROTODIOSCIN RICH EXTRACT OF TRIGONELLA FOENUM-GRAECUM L IN RATS
نویسندگان
چکیده
منابع مشابه
In Vitro Anti-plasmodial activity of Trigonella foenum–graecum L.
Developing countries, where malaria is one of the most prevalent diseases, still rely on traditional medicine as a source for the treatment of this disease. For the present study, Trigonella foenum-graecum L. (fenugreek) were collected from Coimbatore, Tamilnadu, India. The test plant has been used in India by traditional healers for the treatment of fever as well as other diseases. The active ...
متن کاملEvaluation of antifertility activity of Trigonella foenum graecum seeds
Petroleum ether, ethanol and water extracts of Trigonella foenum graecum seeds were investigated separately to determine their antiimplantation (antifertility) and estrogenic/antiestrogenic activity in female albino rats and Swiss mice. Among these, ethanol extract was found to be the most effective as antiimplantation and estrogenic agent. In preliminary phytochemical screening, ethanol extrac...
متن کاملEvaluation of Saponin Rich Fraction of Trigonella Foenum Graecum for Antihypertensive Activity
To separate the saponin rich fraction of Trigonella foenum graecum (TFG) seeds and to evaluate its influence on blood pressure in normal and hypertensive rats. The ethanolic extract of TFG seeds was fractionated with cold diethyl ether to obtain saponin rich fraction. Albino rats of Wistar strain of either sex weighing between 200 to 250 g were used for the hypertension models. Hypertension was...
متن کاملMechanisms responsible for the vascular effect of aqueous Trigonella foenum-graecum leaf extract in diabetic rats
BACKGROUND AND OBJECTIVE Since a beneficial vascular effect of aqueous leaf extract of Trigonella foenum-graecum (TFG) has previously been reported, this study was conducted to evaluate the underlying mechanisms, including the role of nitric oxide (NO) and cyclooxygenase pathways, in diabetic rats. MATERIALS AND METHODS Male Wistar rats were divided into control, extract-treated control, diab...
متن کاملAntidiabetic Activity of Trigonella Foenum- Graecum L. Seeds Extract (ind01) in Neonatal Streptozotocin-induced (n-stz) Rats
The objective of the present investigation was to study antidiabetic activity of standardized extract of Trigonella foenum-graecum seeds (IND01) using neonatal streptozotocin-induced rat (n-STZ) model of diabetes mellitus (DM) in rats for the first time. Streptozotocin (STZ) was injected (50 mg/kg i.p.) in pups of rats in a split dose manner (on 2nd and 3rd postnatal days). After 8 weeks, DM wa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Asian Journal of Pharmaceutical and Clinical Research
سال: 2016
ISSN: 2455-3891,0974-2441
DOI: 10.22159/ajpcr.2016.v9s3.14706